LENScience Senior Biology Seminar Series: “Human aneuploidy and related biotechnologies”

Some XXY people also have Klinefelter Syndrome but not all do. Some XXY people are male, some are female, some are both male and female and some are neither – yet medicine is barely starting to come to terms with the existence of non-male XXY people.

In 2008, 64,343 children were born in New Zealand, 51% male and 49% female. All arose as a result of a successful conception, pregnancy and birth. However, pregnancy isn’t always straightforward and many conceptions do not result in live births or result in live births which bring with them challenges for both parents and child, associated with potential or actual health issues. …

LENScience Senior Biology Seminar Series: Human Aneuploidy and Related Biotechnologies

While aneuploids usually do not survive due to the massive disruption caused to the cells, in the case of the sex chromosomes they will survive. Turner and Klinefelter Syndromes are two examples of this. In the case of Turner Syndrome (XO) it is either the second X or the Y chromosome that is missing. Because in humans only one X chromosome is active in each somatic cell, this situation still leads to a viable embryo, however there are some differences noted in a person with Turner Syndrome. Significantly as a result of undeveloped ovaries they have very low levels of reproductive hormones, secondary sexual characteristics are undeveloped and they are almost always infertile.

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